Maging Sino Ka Man: Ang Pagbabalik

John Lloyd Cruz

as Gabriel "Eli " Hidalgo Roxas

Bea Alonzo

as Jacqueline "Jackie" Madrigal-Roxas

Sam Milby

as Jaime "JB" Roxas Berenguer

Anne Curtis

as Celine Magsaysay Antonio Berenguer

Toni Gonzaga

as Monaliza " Onay" Dimaano / Anna Joy Romualdez

Derek Ramsay

as Joaquin Delos Santos

Angelica Panganiban

as Maria Elena "Lena" Rubio Madrigal

Christopher de Leon

as Fidel Madrigal

Phillip Salvador

as Samuel "Mateo" Romualdez

Vice Ganda

as Joko

Lou Veloso

as Lolo Bogs

Bembol Roco

as Tomas Arroyo

Tommy Abuel

as Daniel Jimenez

Anita Linda

as Impo

Angel Aquino

as Andrea

Malou de Guzman

as Bebeng

Chin Chin Gutierrez

as Corazon Roxas-Romualdez