Lenny The Wonder Dog

Andy Richter

as Lenny

Sammy Kahn

as Zach

Stephanie Sherrin

as Becky

Joe Morton

as Dr. Island

Craig Ferguson

as Dr. Richard Wagner

Michael Winslow

as John Wyndham

Andrew Shaifer

as Hanky

Jeff Chase

as Panky

Evan Adams

as Razel

Oscar Isaac

as Fartman

Rus Blackwell

as Harley

Jeffrey William Evans

as Chief Greenwald

Kathy Kinney

as Lisa Lathers

Damaris Justamante

as Mayor Jenkins

Paola Turbay

as Mrs. Ripley

Camila Banus

as Rainbow

P.C. Martinez

as Bodyguard

Graham Purdy

as Jeremy