Sherlock Holmes

William Gillette

as Sherlock Holmes

Ernest Maupain

as Professor Moriarty

Marjorie Kay

as Alice Faulkner

Edward Fielding

as Dr. Watson

Stewart Robbins

as Benjamin Forman

Hugh Thompson

as Sir Edward Leighton

Ludwig Kreiss

as Baron von Stalburg

Mario Majeroni

as James Larrabee

William Postance

as Sidney Prince

Chester Beery

as Craigin

Fred Malatesta

as 'Lightfoot' McTague

Grace Reals

as Madge Larrabee

Leona Ball

as Therese

Burford Hampden

as Billy

Marian Skinner

as A Suffragette

Edward Arnold

as Moriarty Henchman In Striped Cap

Frank Hamilton

as Tim Leary